[Di-Iodohydroxyquinoline + Metronidazole]
Description / Properties
Metodine used in the treatment of amebiasis (dysentry) and also as an skin antiseptic.
Metodine is primarily indicated in conditions like Amoebiasis, Amoebic liver abscess, Giardiasis.
Di-Iodohydroxyquinoline is known to interact with other drugs like Phenobarbitone, Warfarin (Na). These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
The severe or irreversible adverse effects which give rise to further complications include Hair loss, Thrombocytopenia, Dermatitis, Neutropenia.The symptomatic adverse reactions produced by Di-Iodohydroxyquinoline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Ataxia, Nausea, Vomiting, Diarrhea, Urticaria, Pruritus, Dysuria, Polyuria, Metallic taste, Cystitis, Abdominal discomfort.
Warning and Precautions
Metodine should be used with caution in patients with thyroid disease. Avoid use in patients with neurological disorder, impaired kidney or liver function, and hypersensitive to iodine or halogenated hydroxyquinolones. Discontinue tyreatment if abnormal neurologic signs appear.
Tablets & Syrup
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